Schedule

Eight weeks, online, one session every Saturday from 19:30 to 22:30 (Vietnam time), from 31 October to 19 December 2026: eight sessions of 3 hours (with a 15-minute break), Session n in Week n. There are no groups: the whole class works through every exercise together, and each participant builds their own proposal and manuscript as homework. Weeks 1–4 build understanding and design skills; Weeks 5–8 read the results of the simulated FLUID-ICU dataset through live instructor demos, and each participant writes them up as a manuscript. The whole course is Level 1 (course levels).

Week Session Day Theme You build (homework)
1 Session 1 Saturday 31/10/2026 Ask Proposal: topic, PICO, question, aims
2 Session 2 Saturday 07/11/2026 Find & read Proposal: search, 5 references, problem statement, title
3 Session 3 Saturday 14/11/2026 Design Proposal: design, setting, population
4 Session 4 Saturday 21/11/2026 Bias & effect Proposal: exposure, outcomes, bias plan
5 Session 5 Saturday 28/11/2026 Data Proposal: variables, CRF, data plan · Manuscript: Table 1 understood
6 Session 6 Saturday 05/12/2026 Analyse Proposal: sample size, analysis plan · Manuscript: results interpreted
7 Session 7 Saturday 12/12/2026 Protect & write Proposal: ethics, feasibility, publication plan · Manuscript: Methods + Results
8 Session 8 Saturday 19/12/2026 Publish Manuscript: complete draft · Proposal submitted (about 5 volunteers present)

Detailed timetables

Start Clock* Min Segment
0:00 19:30 20 Welcome, course map, the two individual products, how each session runs, introductions in the chat, how we work online (chat, polls, raise hand), ground rules
0:20 19:50 15 Pre-course quiz (online form)
0:35 20:05 35 1.1 Why research? Anecdote vs evidence, why small numbers mislead, the two course papers (Paper 1 Boulet 2024, Paper 2 Hyun 2023), evidence pyramid, research cycle, types of research, the journey from idea to publication (research vs audit vs QI is in the extra slides)
1:10 20:40 15 BREAK
1:25 20:55 40 1.2 From problem to question: where questions come from, PICO(T) with several worked examples, descriptive vs analytical questions, vague vs answerable, FINER, whole-class task: rescue the running example
2:05 21:35 20 1.3 Aims, objectives, hypotheses (null vs alternative) + quick individual exercise
2:25 21:55 30 Proposal builder 1: the instructor models Part 1 live on the running example (topic, PICO, research question, FINER check, aim and objectives); each participant drafts their own Part 1 (finished as homework); two volunteers share
2:55 22:25 5 Wrap-up, homework

*Times are relative to the start of the session; the clock column shows Vietnam time for the online 19:30–22:30 session. All exercises are done by the whole class together (no groups). [DS] = course-dataset content (FLUID-ICU analysis and manuscript writing).

Open Session 1

Start Clock* Min Segment
0:00 19:30 10 Recap quiz
0:10 19:40 40 2.1 Finding the evidence: search funnel, from PICO to search blocks, Boolean, MeSH, search tools, PubMed vs Google Scholar, live PubMed demo, each participant builds a Boolean search for their own question
0:50 20:20 20 2.2 Managing and citing: reference managers (Zotero demo), citation styles, paraphrasing safely, grey literature & trial registries
1:10 20:40 15 BREAK
1:25 20:55 40 2.3 Reading a paper in 15 minutes: IMRaD, reading order, what an abstract must contain, spin; individual reading task on Paper 1’s abstract (Boulet 2024, RCT; in Course/Papers/)
2:05 21:35 15 2.4 From literature to introduction: literature matrix, problem-statement funnel, working title & keywords
2:20 21:50 35 Proposal builder 2: modelled live (search string, 5 references in the matrix, problem statement, working title); each participant searches and drafts their own (finished as homework); two volunteers share
2:55 22:25 5 Wrap-up

*Times are relative to the start of the session; the clock column shows Vietnam time for the online 19:30–22:30 session. All exercises are done by the whole class together (no groups). [DS] = course-dataset content (FLUID-ICU analysis and manuscript writing).

Open Session 2

Start Clock* Min Segment
0:00 19:30 10 Recap quiz
0:10 19:40 45 3.1 Study designs in pictures: descriptive vs analytical, case report/series, cross-sectional, case-control, cohort, RCT, systematic review/meta-analysis, evidence pyramid, decision tree, strengths & weaknesses, what each design can claim
0:55 20:25 15 Whole-class exercise: Name that design (6 abstracts on the fluid question; poll + chat)
1:10 20:40 15 BREAK
1:25 20:55 30 3.2 More designs: trial variants (parallel, crossover, cluster, factorial; superiority vs non-inferiority), pilot/feasibility, before-after & interrupted time series (QI), qualitative designs; matching design to question
1:55 21:25 15 Whole-class exercise: choose the design for 5 questions (poll); each participant then names the design for their own question in the chat
2:10 21:40 45 Proposal builder 3: inclusion and exclusion criteria, then modelled live (design + justification, setting, population, inclusion/exclusion); each participant drafts their own (finished as homework); three volunteers share in the chat
2:55 22:25 5 Wrap-up

*Times are relative to the start of the session; the clock column shows Vietnam time for the online 19:30–22:30 session. All exercises are done by the whole class together (no groups). [DS] = course-dataset content (FLUID-ICU analysis and manuscript writing).

Open Session 3

Start Clock* Min Segment
0:00 19:30 10 Recap quiz
0:10 19:40 40 4.1 Bias, confounding and causation: random error vs bias, selection, information, confounding (by indication), effect modification, how designs fight bias, validity, reverse causation, Bradford Hill; spot-the-bias quiz
0:50 20:20 25 4.2 Measuring disease and association: prevalence vs incidence, risk, 2×2, RR / OR / RD / NNT, OR vs RR; live 2×2 calculator demo
1:15 20:45 15 BREAK
1:30 21:00 15 Whole-class exercise: two 2×2 calculations, answers by poll
1:45 21:15 30 4.3 Beyond single studies: diagnostic accuracy (sens/spec, PPV & prevalence, ROC), systematic reviews & forest plots, heterogeneity, risk-of-bias tools, “are the conclusions supported?” (whole-class task)
2:15 21:45 40 Proposal builder 4: outcomes, then modelled live (exposure & comparator, outcomes, main biases & mitigation); each participant drafts their own (finished as homework); three volunteers share in the chat
2:55 22:25 5 Wrap-up

*Times are relative to the start of the session; the clock column shows Vietnam time for the online 19:30–22:30 session. All exercises are done by the whole class together (no groups). [DS] = course-dataset content (FLUID-ICU analysis and manuscript writing).

Open Session 4

Start Clock* Min Segment
0:00 19:30 10 Recap quiz
0:10 19:40 35 5.1 Good data by design: variable types, CRF principles, data dictionary, validation, data management (EDC, double entry, audit trail, backups), preventing missing data; whole-class task: fix the CRF items
0:45 20:15 25 5.2 [DS] Meet the course dataset: the FLUID-ICU study, raw vs clean data, the data-quality problems found, live R demo of cleaning and the cleaning log; the five questions Q1 to Q5 introduced (each participant chooses one for their manuscript by the end of Session 6)
1:10 20:40 15 BREAK
1:25 20:55 35 5.3 Describing and showing data: mean/median, SD/IQR, shapes, which graph for which data, good vs bad figures, publication-quality tables, Table 1
2:00 21:30 25 5.4 [DS] Describe the course dataset: live demo of Table 1 and figures; the class reads the FLUID-ICU Table 1 and figures together
2:25 21:55 30 Proposal builder 5: modelled live (variables table, mini-CRF, data dictionary rows, data-management plan); each participant drafts their own variables table (finished as homework)
2:55 22:25 5 Wrap-up

*Times are relative to the start of the session; the clock column shows Vietnam time for the online 19:30–22:30 session. All exercises are done by the whole class together (no groups). [DS] = course-dataset content (FLUID-ICU analysis and manuscript writing).

Open Session 5

Start Clock* Min Segment
0:00 19:30 10 Recap quiz
0:10 19:40 40 6.1 From sample to population: CI, p-values & misinterpretations, one-sided vs two-sided tests, type I/II errors, power, sample size (5-minute live demo), choosing a test (decision table), paired vs unpaired, multiple comparisons
0:50 20:20 20 6.2 [DS] Compare groups in the course dataset: live demo (t-test / Mann-Whitney / chi-square); the class interprets the outputs together (Q1 in full, Q2 to Q5 briefly)
1:10 20:40 15 BREAK
1:25 20:55 35 6.3 Relationships and models: correlation, linear and logistic regression, adjustment, reading a regression table, overfitting, censoring and Kaplan-Meier curves (prediction/ML and interaction in the extra slides)
2:00 21:30 25 6.4 [DS] Model the course dataset: the SAP that was written before the analysis, crude vs adjusted OR (confounding by indication made visible), Kaplan-Meier + Cox HR, complete-case vs multiple imputation
2:25 21:55 30 Proposal builder 6: modelled live (sample size, analysis plan, confounders, missing-data plan); each participant drafts their own sample-size inputs (finished as homework)
2:55 22:25 5 Wrap-up

*Times are relative to the start of the session; the clock column shows Vietnam time for the online 19:30–22:30 session. All exercises are done by the whole class together (no groups). [DS] = course-dataset content (FLUID-ICU analysis and manuscript writing).

Open Session 6

Start Clock* Min Segment
0:00 19:30 10 Recap quiz
0:10 19:40 30 7.1 Protocol, ethics and consent: protocol (SPIRIT), Helsinki & GCP, ethics committee journey, registration, consent incl. ICU consent, confidentiality, feasibility
0:40 20:10 20 7.2 Research integrity: FFP, duplicate/salami, authorship, conflicts of interest, data sharing, AI use; scenario poll
1:00 20:30 15 Proposal builder 7: modelled live (ethics, registration, feasibility, publication plan); participants draft their own Part 4 as homework
1:15 20:45 15 BREAK
1:30 21:00 35 7.3 Writing the paper (I): writing order, Methods (incl. statistical paragraph), Results (participants first, numbers with CIs, no interpretation), stand-alone tables & figures, STROBE for the course-dataset paper
2:05 21:35 45 [DS] Manuscript workshop 1: the instructor drafts Methods + Results for Q1 live with the class (30 min); each participant then starts the Methods + Results (~600 words) for their chosen question, with Table 1 and one figure/table from its results pack (15 min, finished as homework)
2:50 22:20 10 Key words, wrap-up, exit question, homework

*Times are relative to the start of the session; the clock column shows Vietnam time for the online 19:30–22:30 session. All exercises are done by the whole class together (no groups). [DS] = course-dataset content (FLUID-ICU analysis and manuscript writing).

Open Session 7

Start Clock* Min Segment
0:00 19:30 5 Recap
0:05 19:35 25 8.1 Writing the paper (II): Introduction funnel, Discussion six moves, calibrated language, abstract, title & keywords, before you submit
0:30 20:00 30 [DS] Manuscript workshop 2: Introduction, Discussion, Abstract and Title modelled live on Q1 (22 min); each participant writes their own aim and title (8 min) and completes their draft as homework
1:00 20:30 20 8.2 Getting published: reporting guidelines (EQUATOR demo), choosing a journal, predatory journals, submission package, peer review, responding to reviewers (preprints, rejection, proofs and conference abstracts in the extra slides)
1:20 20:50 15 BREAK
1:35 21:05 25 8.3 Be the reviewer: simplified appraisal of Papers 1 and 2 (Boulet 2024 RCT and Hyun 2023 cohort, in Course/Papers/) with the whole class, using the 10-question checklist, as training for the individual peer review after the course
2:00 21:30 45 Volunteer presentations: about 5 volunteers present their own research proposal + publication plan (6 min + 2 min feedback each), then a 5-minute closing round; everyone submits slides and the written proposal
2:45 22:15 15 Post-course quiz, evaluation, next steps (individual peer review of one peer’s manuscript as homework)

*Times are relative to the start of the session; the clock column shows Vietnam time for the online 19:30–22:30 session. All exercises are done by the whole class together (no groups). [DS] = course-dataset content (FLUID-ICU analysis and manuscript writing).

Open Session 8